Practical guide
Plan without surprises
Walk to Sforza Castle
From the museum, cross the Magenta district toward Sforza Castle. Choose its museums if time allows, or pass through the courtyards and continue into Parco Sempione.
Castle to Duomo
Via Dante leads toward Cordusio and Piazza del Duomo. Reserve cathedral and rooftop admission separately and keep it well clear of the Last Supper slot.
Brera and Leonardo themes
The Pinacoteca di Brera makes a strong art-focused extension. Leonardo3 near the Galleria uses models and reconstructions to explore Leonardo’s inventions; it does not display original material from the Last Supper.
A short itinerary
With half a day, focus on Santa Maria delle Grazie, the Last Supper, Sforza Castle, and the walk to the Duomo. Add another museum only with safely spaced reservations and a break.